NOS2 and astrocytoma (excluding glioblastoma): A water-soluble form of chitosan inhibited the production of proinflammatory cytokines including TNFα and IL-6 as well as inducible nitric oxide synthase (iNOS) in human astrocytoma cell line CCF-STTG1 stimulated with IL-1β and Aβ fragments (25–35) [37].