ILC2s play a role in the production of pro-inflammatory cytokines, and overexpression of the transcription factor GATA3 increased the expression of stimulation-expressed gene 2 (ST2) and thymic stromal lymphopoietin (TSLP) receptors in the human pulmonary ILC2, leading to the development of asthma [85,86]. This evidence concerns the gene TSLP and asthma.