Comparison of the detection rate of ctDNA between mutational targets demonstrated no significant difference between ctDNA levels and detection rate (geometric mean: 19.2 copies/mL, 67/100, 67%) in patients with BRAF versus patients with other melanoma-associated mutations (geometric mean: 13.7 copies/mL, 26/42, 62%; Figure 1C). Here, BRAF is linked to melanoma.