In addition, mutations of calcium channels have been found in ASD, for example, CACNA1A rs7249246/rs12609735 were associated with Chinese Han ASD [109], and CACNA1A mutations in Epileptic Encephalopathy [110, 111], gain of function of CACNA1C in Timothy syndrome with ASD [112] and recurring CNVs of CACNA2D3 [29, 36, 113, 114]. The gene discussed is CACNA1C; the disease is Epileptic encephalopathy.