Exome sequencing has identified various mutations of CACNA1D in ASD [14, 16, 29, 36, 115], epilepsy [116] developmental delay [117] endocrine issues [117, 118], CACNA2D1 in epilepsy and intellectual disability [119] and CACNB2 mutations in ASD [120, 121]. This evidence concerns the gene CACNA2D1 and Intellectual disability.