When comparing EVs from patients with sepsis and renal failure with EVs from septic patients without renal failure, Tokes-Fuzesi et al. identified increased total PS+ EVs, PS+ plt-EVs, and PS+/CD13+ myeloid EVs on the day of admission in the blood of patients who already developed AKI by that time [57]. The gene discussed is ANPEP; the disease is acute kidney injury.