Zymogen granule protein 16B(ZG16B), also identified as Pancreatic adenocarcinoma upregulated factor, is a paralog of ZG16A which has a 65.5% of similarity and 36% identity, first found to be overexpressed in pancreatic ductal adenocarcinoma [19,20,21]. This evidence concerns the gene ZG16B and pancreatic ductal adenocarcinoma.