Using gene–gene correlation analyses, we found that the expression of GABRD was significantly correlated with those of EMT markers (except that of CDH1/E-cadherin) and VEGFA and its two receptors, suggesting that EMT and angiogenesis could be the future directions to fully understand the mechanism of GABRD in CRC carcinogenesis. The gene discussed is GABRD; the disease is colorectal carcinoma.