Results of wound healing assay also demonstrated that the migratory distance of CRC cell lines was widened in the si-SRPX2 group (P < 0.05) (Figure 4d), and the number of invasive PC cells also dropped markedly in the si-SRPX2 group in comparison to NC group (P < 0.05) (Figure 4e). Here, SRPX2 is linked to colorectal carcinoma.