The number of risk factors considered (age > 65, CK ≥ 180, and CD4+ cell counts <300) was included in a Cox proportional hazards model and adjusted for symptoms at admission, including body mass index, ribavirin use, lopinavir/ritonavir use, antibiotic use, dyspnea, comorbid diabetes, comorbid hypertension, platelet count, C-reactive protein, lactate dehydrogenase, aspartate aminotransferase, albumin, Beta-2 microglobulin, eGFR, PaO2/FiO2, and CD8+ T-cell counts. The gene discussed is CD8A; the disease is Hypertension.