The top 30 DEGs, including IGLV2-14, MZB1, CD27, POU2AF1, CD72, PDCD1, HSH2D, PRF1, SIT1, LY9, PLA2G2D, IGLV2-8, RNF39, CXCL9, CD38, CXCR2P1, SIRPG, IGKV4-1, FCRL5, RAB37, ADAMDEC1, LCK, IGLV3-21, IGHV3-15, IGHM, IGLC2, ITGAL, RHOH, IGLC3, and ICAM3, were chosen as the potential risk factors for the prognosis of patients with metastatic tumors (Table 1). The gene discussed is ICAM3; the disease is metastatic neoplasm.