CD40LG and atrial fibrillation: In addition, there was a graded increase in the levels of the inflammatory biomarkers across the healthy subjects, NSR and various AF subgroups (Figure 2).The levels of significant risk factors, that is, inflammatory biomarkers (hs‐CRP, IL‐6, sCD‐40L), age, MVA, Wilkins score were dichotomized for the purpose of regression analysis, using the cut‐offs values with optimum sensitivity and specificity derived by constructing receiver operating characteristic curves (Table S2, S3).