ITGA2 (HR = 0.68, P < 0.025), ITGA5 (HR = 1.43, P < 0.031), ITGA11 (HR = 1.52, P < 0.013), ITGAV (HR = 1.86, P < 0.001), ITGB1 (HR = 1.49, P < 0.016) were higher in patients with short OS compared to their expression in patients with longer OS, and the OS of GC patients with high expression of these genes was significantly shortened (Figure 5). The gene discussed is ITGA5; the disease is gastric cancer.