A more attractive candidate is IFN induced protein with tetratricopeptide repeats 3 (IFIT3) (Figure 1), which is highly up-regulated in SARS-CoV-2 infected bronchial epithelial cells (101): IFIT3 interacts with both STING and TANK-binding kinase 1 genes, and activate them in some disorders like lupus (102). The gene discussed is STING1; the disease is systemic lupus erythematosus.