Different gene expression levels were also observed in GRB7 (P = 0.001), HER2 (P = 0.001), BCL2 (P = 0.006), SCUBE (P = 0.030) and BAG1 (P = 0.008), although the expression of these genes was not different between the IDC and IDC/DCIS groups. Here, SCUBE2 is linked to ductal breast carcinoma in situ.