Data presented by Farrokhi et al.58 suggests that the leptin difference between multiple sclerosis (MS) patients and age-sex-matched controls (Fig. 7A histogram) was significantly greater in GG homozygotes (difference ± SE: 8.30 ± 0.69 ng/ml) than in AA homozygotes (5.49 ± 0.67, P = 0.003) or AG heterozygotes (5.14 ± 0.69 ng/ml, P = 0.001) of LEP rs7799039 polymorphism. The gene discussed is LEP; the disease is multiple sclerosis.