Finally, comparison of the reduction in ADM-R225-hnRNP-A1 in mouse blood (Fig. 6B) to that observed in tumor xenografts demonstrates similar reduction in ADMA-hnRNPA1 in tumor and circulation following multiple days of GSK3368715 treatment using these distinctly different assays (Fig. 8G). The gene discussed is HNRNPA1; the disease is neoplasm.