ST1326, a novel inhibitor of CPT1A, suppresses cell growth and induces mitochondrial damage and apoptosis in primary AML cells (Fig. 6).346 Several other inhibitors of FAO that work either directly or indirectly have been tested in other liquid cancers and solid tumors,347 but this strategy has yet to be confirmed against AML LSCs. The gene discussed is CPT1A; the disease is acute myeloid leukemia.