STC2 and metabolic dysfunction-associated steatohepatitis: Transcriptomic analysis revealed upregulation of genes in the ER stress-unfolded protein response (UPR) axis including stanniocalcin-2 (STC2), a pro-survival component, and fibroblast growth factor 21 (FGF21), a marker of hepatic fat, targets that are increased in NASH patients [36].