Thus, the most significant indicators affecting the composition of saliva in COPD are the activity of enzymes (LDH, catalase) (Figure 1B), then the level of lipid peroxidation products (diene conjugates, Schiff bases) (Figure 1D) and the value of AST/ALT-ratio are significant (Figure 1F). This evidence concerns the gene CAT and chronic obstructive pulmonary disease.