Lastly, in our study, IFN-induced ADRs were mainly related to the SOCs “Blood and lymphatic system disorders” (n = 11; median TTE: 1518) that include cases of leucopenia and neutropenia and “General disorders and administration site conditions” (n = 24; median TTE: 188), mainly represented by flu-like symptoms. This evidence concerns the gene IFNA1 and Decreased total neutrophil count.