Our study has also detected alterations in the expression of EED (a polycomb repressive complex 2 gene) and IL26 (a member of the IL10 superfamily which has a role in host innate immune response and is overexpressed in T-cells with proinflammatory properties); both genes differentially expressed in CTCL and benign skin biopsies [36]. This evidence concerns the gene IL10 and primary cutaneous T-cell non-Hodgkin lymphoma.