These include the phosphatidylinositol-3-kinase (PI3K)/AKT signaling pathway in hepatocellular carcinoma and colon cancer [16,17], Bcl-2 family in lung cancer [18], caspases in breast cancer [19], cyclins in cervical cancer [20], and cytochrome c in osteosarcoma [21]. The gene discussed is AKT1; the disease is lung carcinoma.