In the TCGA pan-cancer cohort, PTEN alterations occur most frequently in uterine corpus endometrial carcinoma (UCEC) (66.54% of all UCEC samples; data not shown), while FLG-AS1 amplification is most prevalent in hepatocellular carcinoma, lung adenocarcinoma and breast invasive carcinoma (Figure S2), with only two UCEC samples harboring an amplification in this lncRNA. This evidence concerns the gene PTEN and lung adenocarcinoma.