High expression levels of CTSB have been observed in various cancers such as breast, esophageal, gastric, colon, and pancreatic cancers, and hepatocellular carcinoma, and both advanced stage and poor survival in multiple cancers are known to be associated with greater expression of CTSB [20,21,22,23]. The gene discussed is CTSB; the disease is familial pancreatic carcinoma.