We also investigated blood parameters (number of erythrocytes and leukocytes, differential leukocyte count, hemoglobin content, mean cell hemoglobin (MHC), erythrocyte resistance to acid hemolysis), parameters associated with carbonyl/oxidative stress (levels of ROS, reduced glutathione (GSH), thiobarbituric acid reactive substances (TBA-RS), OMPs, AOPPs, AGEs) and activity of antioxidant enzymes (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR)) in leukocytes of rats with streptozotocin-induced DM. Here, SOD1 is linked to diabetes mellitus.