Overall, Munc18‐1 encephalopathies are associated with epilepsy, severe to profound intellectual disability, developmental delay, ataxia, tremor, and other neurological symptoms (Saitsu et al, 2008; Milh et al, 2011; Stamberger et al, 2016; Suri et al, 2017). This evidence concerns the gene STXBP1 and Intellectual disability.