TNXB and congenital adrenal hyperplasia: A TNXB c.12218G>A (p.Arg4073His) variant in family A is commonly predicted in silico as damaging or pathogenic by altering TNX protein folding (Chen et al., 2016), thus the CAH‐X phenotype in subjects A‐II‐1 and A‐II‐2 might be due to biallelic TNXB defects.