CD163 and Parkinson disease: Again, the estimated amount of sCD163 in CSF with serum origin was similar across groups (late PD: 0.011 ± 0.002, early PD: 0.014 ± 0.002, HCs: 0.009 ± 0.002), whereas the intrathecally produced sCD163 increased in late PD (0.109 ± 0.047) versus early PD (0.071 ± 0.018, P = 0.004) and versus HCs (0.074 ± 0.023, P = 0.02).