In serum, the sCD163 correlations were weaker and fewer (Fig. 4C,D): serum‐sCD163 was correlated with CRP (r = 0.41), IL‐6 (r = 0.39), ICAM‐1 (r = 0.34), and SAA (r = 0.35) in all patients and with TNF‐α (r = 0.55), IL‐12/IL‐23p (r = 0.47), and VCAM‐1 (r = 0.57), correlating at late PD. This evidence concerns the gene CRP and Parkinson disease.