RECQL5 and bladder transitional cell carcinoma: Elevated RECQ5 expression is linked to urothelial bladder carcinoma, which affects ∼400 000 people annually (22), moreover, the RECQ5 gene is frequently amplified in human cancers and even moderate overexpression of RECQ5 in human cell lines can lead to dysregulation of homologous recombination (23).