BRCA2 and breast carcinoma: Even though a higher frequency of PVs in BRCA2 than BRCA1 have been found in the general population[41], this does not explain why multiple studies have identified so few PVs in BRCA1, which, in the Danish population, are more frequently associated with breast cancer than PVs in BRCA2.[42,43] Overall, WGS data from ethnically comparable children are lacking making comparisons of genetic findings in patients difficult.