CAD and autism: The frequency of PVs in our study was significantly higher than that observed in control cohorts wherein 0.6–1.1% of adult patients in a Genomics England cohort and a cohort of pediatric and adult patients with autism had PVs in CPS genes.[7] This study, however, excluded patients with known CPS and included different genes (including genes with frequent somatic variants) and is thus not directly comparable.