Despite the recognized importance of T-CD4+ counts in evaluating the disease status at ART initiation, ART could have been initiated without performing a T-CD4+ count by the symptomatic patients who presented late for HIV/AIDS care (especially in the first years of the study period) or those who were clinically stable but did not perform T-CD4+ counts in view of the recommendation of early initiation of ART. This evidence concerns the gene CD4 and AIDS.