FLT3 and acute myeloid leukemia: In addition, univariate Cox proportional hazards regression model analysis showed that KIF2A high expression (P<0.001), WBC >10×109/L (P=0.002), monosomal karyotype (P<0.001), FLT3-ITD mutation (P=0.008), and high risk stratification were associated with shorter EFS; multivariate Cox proportional hazards regression model analysis displayed that WBC >10×109/L (P=0.000) and high risk stratification were independent predictive factors for shorter EFS in AML patients (Table 3).