FTO and Alzheimer disease: Likewise, FTO immunostaining were consistently increased in human AD and AA tissues compared with that in control, and the percentages of FTO-positive cells were significantly higher in AD and AA than that in control (AD: 46.7 ± 8.0%, AA: 83.3 ± 9.1% vs. Control: 10.3 ± 5.5%, P < 0.05, and P < 0.01, respectively).