MAP2K4 and cancer: From the high-BPA group (average urinary BPA = 17.5 ± 11.2 ng/g- creatinine adjusted), several factors associated with cancer are increased and include ankyrin 2, a cytoskeletal protein involved in metastasis and migration; antigen Ki-67, which participates in cell proliferation; and E3 ubiquitin-ligase, talin 2, transient receptor potential channel 5 (TRPC5), mitogen-activated kinase kinase 4 (MKK4), and zinc finger 185 which are involved in cancer development.