Accordingly, IFNpos SLE patients, in addition to the activation of senescent T-cells, presented high serum levels of several inflammatory cytokines and chemokines, including IL-6, IFNγ, ICAM-1, CXCL10, CCL2, and CCL3, than their IFNneg counterparts. The gene discussed is IL6; the disease is systemic lupus erythematosus.