Heart function was measured by echocardiography in mice which received implantation of control medium (Media), control vector-transfected O hBM-MSCs (O-c), or CYP7A1-1 downregulated O hBM-MSCs (O-sh-CYP7A1), into the border region immediately after MI. This evidence concerns the gene CYP7A1 and myocardial infarction.