ITGB1 and neoplasm: Further support for the tumor suppressive role of miR-124-3p was provided by Hunt et al. (2011) who reported decreased migration and invasion in oral squamous cell carcinoma, following miR-124-3p knockdown of ITGB1. Vimentin (VIM) is central to cytoskeletal modulation associated with EMT and a key determinant of non-neuronal morphology.