AHR and cancer: Although the involvement of miR-124-3p in proliferation, invasion and apoptosis has been demonstrated across a range of cancers, the current knowledge of its effect in neuroblastoma is limited, with reports of knockdown of miR-124-3p in SK-N-SH neuroblastoma cells inducing differentiation, cell cycle arrest and apoptosis through promoting the aryl hydrocarbon receptor (AHR) (Huang et al., 2011).