Pulse selection with cisplatin in these cell lines resulted in a significant up-regulation of VIM in SK-N-ASCis24 and downregulation of NEFL, CgA, and GAP43; however, the KellyCis83 demonstrated increased expression of CgA and GAP43, along with a substantial decrease in the expression of VIM (Supplementary Material S7), suggesting a phenotypic divergence of the cell lines in response to chemotherapeutic treatment, supporting the commitment of adrenergic-type neuroblastoma cells to the adrenergic lineage as reported by van Groningen et al. (2019). The gene discussed is GAP43; the disease is neuroblastoma.