The cytoskeletal genes MYH9, PLEC, ITGB1, VIM, and ACTN4, were previously reported by our lab to drive EMT-like morphological transformation and increased invasiveness (2.5 fold) in the MES SK-N-ASCis24 neuroblastoma cell line, coinciding with resistance development (Piskareva et al., 2015). This evidence concerns the gene PLEC and neuroblastoma.