ITGB1 and non-small cell lung carcinoma: Using A549 and H1299 human NSCLC cell lines, L9981 and 95D highly metastatic NSCLC cell lines, and NL9980 and 95C low-metastatic NSCLC cell lines., the authors observed that knockdown of long non-coding RNA linc-ITGB1 inhibited the expression of various markers of cancer stemness and CSC formation by reducing the expression of the EMT-related transcription factor Snail.