FOXM1 and familial pancreatic carcinoma: Hypoxia-driven phosphorylated glycoprotein such as osteopontin, promoted stem cell-like properties and EMT in pancreatic cancer cells in a paracrine manner, through integrin αvβ3-Akt/Erk- forkhead box protein M1 (FOXM1) signaling (Cao et al., 2019).