EGFR and cancer: In addition to its application in environmental pollution, an electrochemical sensing platform based on COFs also plays a prominent role in biomedicine, such as epidermal growth factor receptors, living cancer cells, prostate specific antigens, cardiac troponin I, glucose, ascorbic acid, dopamine, uric acid, guanine, adenine, luteolin, hydrogen peroxide, chlorogenic acid, furazolidone, tanshinol, sulfadiazine, and acetaminophen.