IPEX is an inborn error of immunity classically caused by mutations on the X-linked gene FOXP3, that codes for a transcriptional factor essential for the maintenance of thymus-derived regulatory T cells, or Treg (18, 19), which suppress autoimmune responses, hence, maintaining homeostasis and tolerance (20). Here, FOXP3 is linked to immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome.