CCND1 and neoplasm: Promote the overexpression of nuclear factor kappa-light-chain-enhancer of activated B cells and the activation of cyclin-D1, an epidermal growth factor receptor ligand that promote the growth of tumors, eventually provoking nuclear translocation; epithelial mesenchymal transformation in malignant cells, tumor proliferation and tumor invasion (Hoppe et al., 2016; Lafuente Ibanez de Mendoza et al., 2019).