The expression of Tim3 on MM cell lines RPMI-8226 and U266 was significantly higher than that in the normal control group (89.327±1.359% vs. 7.665±3.592%, p<0.001; 59.263±3.129% vs. 7.665±3.592%, p<0.001; show in Figures 2A, B). The gene discussed is HAVCR2; the disease is Miyoshi myopathy.