A positive immunohistochemical reaction for WNT10A, Fzd5, β-catenin, GSK-3ß, CacyBP/SIP, and LMP7 was observed in all studied kidneys tissues, although the intensity of immunoreaction varied between non-malignant kidney and RCC tissue samples, depending on the histological type of the tumor (Figures 1–6). Here, FZD5 is linked to renal cell carcinoma.