IRF1, PSMB9, TAP1, ETV7, and PSMB10 were related to CD8+ T cell infiltration proportion in thyroid carcinoma, breast invasive carcinoma, head and neck squamous cell carcinoma, hepatocellular carcinoma, lung adenocarcinoma, and skin cutaneous melanoma (Table 5). The gene discussed is IRF1; the disease is head and neck squamous cell carcinoma.