PGR and breast cancer: The second also comprises four miRs (miR-155, miR-27a, miR-30e, and miR-493) and is linked to BC classification based on ER/PR/HER2/basal cytokeratin/EGFR status as well as separation of cases into low- and high-risk categories (50) with the ability to predict patient response to therapy with the two most common systemic protocols used to treat TNBC (anthracycline or anthracycline plus taxanes) (146).