This approach was retried within a 313-protein network for Troyer syndrome, a human disease also known as human spastic paraplegia 20 (HSP20) and here high confidence interactions (0.75) of two candidate genes UV Stimulated Scaffold Protein A (UVSSA) and LOC100848076 to gene products in the disease network were identified (Figure 3). Here, HSPB6 is linked to Troyer syndrome.