It is conceivable that LOC10084876 might interact with REEP1, 2, or 5. Mutations in REEP1 are causative for human autosomal dominant spastic paraplegia 31 (Schlang et al., 2008; Richard et al., 2017) and mutations in REEP2 are causative for spastic paraplegia 72 in humans (Esteves et al., 2014). Here, REEP2 is linked to Autosomal dominant spastic paraplegia type 31.