Among them, nine genes (AURKB, CDKN2A, E2F1, ERP29, HSF1, NSMF, MSX1, STX4, and NLRP12) were upregulated, while the other two genes (PHLDA3 and BTG2) were downregulated in the PCa tissues. The gene discussed is CDKN2A; the disease is posterior cortical atrophy.