Furthermore, our results are confirmed by the literatures, with 6 out of top 10 features associated with specific cancers including NKIRAS1 (Gerashchenko et al., 2010; Khodyrev et al., 2012), CDKN2B (Clavell et al., 2008), YTHDC2 (Wittliff et al., 2015; Yu et al., 2020), MECOM (Choi et al., 2017), RBFOX1 (Sengupta et al., 2013), and RAB6B (Kou et al., 2015). This evidence concerns the gene CDKN2B and cancer.