Two DElncRNAs (GVINP1 and PCED1B-AS1), two DEmiRNAs (hsa-let-7c-5p and hsa-miR-150-5p), and 17 DEmRNAs (BIN2, CCDC69, CCR4, CD3E, CD5, CD48, DOCK2, F2RL2, HLA-E, IKZF1, JCHAIN, LRRC15, NCKAP1L, PIK3CD, SFRP1, SPN, and TNFAIP3) were found to be closely related to the overall survival of luminal BC patients (p < 0.05; Figure 6). The gene discussed is SPN; the disease is breast cancer.