CHRNA3 SNVs have not been found to be significantly associated with hypertension risks in many genome-wide association studies (Wellcome Trust Case Control Consortium, 2007; Adeyemo et al., 2009; Levy et al., 2009; Org et al., 2009; Hiura et al., 2010; Padmanabhan et al., 2010; International Consortium for Blood Pressure Genome-Wide Association Studies et al., 2011; Slavin et al., 2011; Guo et al., 2012). Here, CHRNA3 is linked to hypertensive disorder.